Dr. Mark, First of all a hearty thank-you to Dr. Manhart. I have only been using the toothbrush and oral-cal for 2 weeks and can already notice a difference. The constant pain has gone, the tingly gums gone, my bite pattern has largely normalized. Today I even realized I was chewing on the side of my mouth I’ve been avoiding for many months. I also notice my night-time grinding seems to have stopped. – LB in CA